A NOVEL P53 BYSTANDER EFFECT INDUCES GLIOBLASTOMA CELL DEATH THROUGH A GLYCOSYLATION-DEPENDENT MECHANISM

BACKGROUND: Mutations in the TP53 tumor suppressor gene are required for the development of many malignancies, including brain tumors. Yet, the molecular mechanisms underlying p53's anti-tumor effects remain incompletely understood. In the present study we demonstrate the existence of a novel c...

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Main Authors: Van Meir, Erwin G., Lee, Sok-Hyong, Khwaja, Fatima W., Zerrouqi, Abdessamad, Zhang, Zhaobin, Olson, Jeffrey J., Kaluzova, Milota, Hadjipanayis, Costas G., Devi, Narra S.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144540/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.70
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