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Targeted therapy of glioblastoma stem-like cells and tumor non-stem cells using cetuximab-conjugated iron-oxide nanoparticles

Malignant gliomas remain aggressive and lethal primary brain tumors in adults. The epidermal growth factor receptor (EGFR) is frequently overexpressed in the most common malignant glioma, glioblastoma (GBM), and represents an important therapeutic target. GBM stem-like cells (GSCs) present in tumors...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kaluzova, Milota, Bouras, Alexandros, Machaidze, Revaz, Hadjipanayis, Costas G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496184/
https://ncbi.nlm.nih.gov/pubmed/25871395
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