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Radiosensitivity enhancement of radioresistant glioblastoma by epidermal growth factor receptor antibody-conjugated iron-oxide nanoparticles

The epidermal growth factor receptor deletion variant EGFRvIII is known to be expressed in a subset of patients with glioblastoma (GBM) tumors that enhances tumorigenicity and also accounts for radiation and chemotherapy resistance. Targeting the EGFRvIII deletion mutant may lead to improved GBM the...

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Bouras, Alexandros, Kaluzova, Milota, Hadjipanayis, Costas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498963/
https://ncbi.nlm.nih.gov/pubmed/25981803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-015-1807-0
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