טוען...

Selective Detection of the D-enantiomer of 2-Hydroxyglutarate in the CSF of Glioma Patients with Mutated Isocitrate Dehydrogenase

PURPOSE: Elevation in D-2-Hydroxyglutarate (D-2HG) has recently emerged as a mandatory byproduct of mutated Isocitrate Dehydrogenase (IDH) genes 1 and 2 in glioma patients. The goal of the present study was to demonstrate the feasibility of detection of elevated levels of D-2HG in the cerebrospinal...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Clin Cancer Res
Main Authors: Kalinina, Juliya, Ahn, Jun, Devi, Narra S., Wang, Liya, Li, Yuancheng, Olson, Jeffrey J., Glantz, Michael, Smith, Thomas, Kim, Ella L., Giese, Alf, Jensen, Randy L., Chen, Clark C., Carter, Bob S., Mao, Hui, He, Miao, Van Meir, Erwin G.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443654/
https://ncbi.nlm.nih.gov/pubmed/27340277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2965
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