The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells

Yazar: Lee, Ciaran M, Cradick, Thomas J, Bao, Gang
Yayımlandı Mol Ther (2016)

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

Yazar: Cradick, Thomas J., Fine, Eli J., Antico, Christopher J., Bao, Gang
Baskı/Yayın Bilgisi 2013

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

Yazar: Lee, Ciaran M, Cradick, Thomas J, Fine, Eli J, Bao, Gang
Yayımlandı Mol Ther (2016)

Nanomedicine: Tiny Particles and Machines Give Huge Gains

Yazar: Tong, Sheng, Fine, Eli J., Lin, Yanni, Cradick, Thomas J., Bao, Gang
Baskı/Yayın Bilgisi 2013

ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites

Yazar: Cradick, Thomas J, Ambrosini, Giovanna, Iseli, Christian, Bucher, Philipp, McCaffrey, Anton P
Baskı/Yayın Bilgisi 2011

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

Yazar: Fine, Eli J., Cradick, Thomas J., Zhao, Charles L., Lin, Yanni, Bao, Gang
Baskı/Yayın Bilgisi 2014

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

Yazar: Cradick, Thomas J, Qiu, Peng, Lee, Ciaran M, Fine, Eli J, Bao, Gang
Yayımlandı Mol Ther Nucleic Acids (2014)

Zinc-finger Nucleases as a Novel Therapeutic Strategy for Targeting Hepatitis B Virus DNAs

Yazar: Cradick, Thomas J, Keck, Kathy, Bradshaw, Shannon, Jamieson, Andrew C, McCaffrey, Anton P
Baskı/Yayın Bilgisi 2010

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

Yazar: Mussolino, Claudio, Alzubi, Jamal, Fine, Eli J., Morbitzer, Robert, Cradick, Thomas J., Lahaye, Thomas, Bao, Gang, Cathomen, Toni
Baskı/Yayın Bilgisi 2014

SAPTA: a new design tool for improving TALE nuclease activity

Yazar: Lin, Yanni, Fine, Eli J., Zheng, Zhilan, Antico, Christopher J., Voit, Richard A., Porteus, Matthew H., Cradick, Thomas J., Bao, Gang
Baskı/Yayın Bilgisi 2014

Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome

Yazar: Müller, Maximilian, Lee, Ciaran M, Gasiunas, Giedrius, Davis, Timothy H, Cradick, Thomas J, Siksnys, Virginijus, Bao, Gang, Cathomen, Toni, Mussolino, Claudio
Yayımlandı Mol Ther (2016)

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

Yazar: Lin, Yanni, Cradick, Thomas J., Brown, Matthew T., Deshmukh, Harshavardhan, Ranjan, Piyush, Sarode, Neha, Wile, Brian M., Vertino, Paula M., Stewart, Frank J., Bao, Gang
Baskı/Yayın Bilgisi 2014

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

Yazar: Ramirez, Cherie L., Certo, Michael T., Mussolino, Claudio, Goodwin, Mathew J., Cradick, Thomas J., McCaffrey, Anton P., Cathomen, Toni, Scharenberg, Andrew M., Joung, J. Keith
Baskı/Yayın Bilgisi 2012

Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection

Yazar: Ye, Lin, Wang, Jiaming, Beyer, Ashley I., Teque, Fernando, Cradick, Thomas J., Qi, Zhongxia, Chang, Judy C., Bao, Gang, Muench, Marcus O., Yu, Jingwei, Levy, Jay A., Kan, Yuet Wai
Baskı/Yayın Bilgisi 2014

DNA targeting specificity of RNA-guided Cas9 nucleases

Yazar: Hsu, Patrick D, Scott, David A, Weinstein, Joshua A, Ran, F Ann, Konermann, Silvana, Agarwala, Vineeta, Li, Yinqing, Fine, Eli J, Wu, Xuebing, Shalem, Ophir, Cradick, Thomas J, Marraffini, Luciano A, Bao, Gang, Zhang, Feng
Baskı/Yayın Bilgisi 2013

TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs

Yazar: Suzuki, Shingo, Sargent, R Geoffrey, Illek, Beate, Fischer, Horst, Esmaeili-Shandiz, Alaleh, Yezzi, Michael J, Lee, Albert, Yang, Yanu, Kim, Soya, Renz, Peter, Qi, Zhongxia, Yu, Jingwei, Muench, Marcus O, Beyer, Ashley I, Guimarães, Alessander O, Ye, Lin, Chang, Judy, Fine, Eli J, Cradick, Thomas J, Bao, Gang, Rahdar, Meghdad, Porteus, Matthew H, Shuto, Tsuyoshi, Kai, Hirofumi, Kan, Yuet W, Gruenert, Dieter C
Yayımlandı Mol Ther Nucleic Acids (2016)