The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells

af Lee, Ciaran M, Cradick, Thomas J, Bao, Gang
Udgivet i Mol Ther (2016)

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

af Cradick, Thomas J., Fine, Eli J., Antico, Christopher J., Bao, Gang
Udgivet 2013

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

af Lee, Ciaran M, Cradick, Thomas J, Fine, Eli J, Bao, Gang
Udgivet i Mol Ther (2016)

Nanomedicine: Tiny Particles and Machines Give Huge Gains

af Tong, Sheng, Fine, Eli J., Lin, Yanni, Cradick, Thomas J., Bao, Gang
Udgivet 2013

ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites

af Cradick, Thomas J, Ambrosini, Giovanna, Iseli, Christian, Bucher, Philipp, McCaffrey, Anton P
Udgivet 2011

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

af Fine, Eli J., Cradick, Thomas J., Zhao, Charles L., Lin, Yanni, Bao, Gang
Udgivet 2014

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

af Cradick, Thomas J, Qiu, Peng, Lee, Ciaran M, Fine, Eli J, Bao, Gang
Udgivet i Mol Ther Nucleic Acids (2014)

Zinc-finger Nucleases as a Novel Therapeutic Strategy for Targeting Hepatitis B Virus DNAs

af Cradick, Thomas J, Keck, Kathy, Bradshaw, Shannon, Jamieson, Andrew C, McCaffrey, Anton P
Udgivet 2010

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

af Mussolino, Claudio, Alzubi, Jamal, Fine, Eli J., Morbitzer, Robert, Cradick, Thomas J., Lahaye, Thomas, Bao, Gang, Cathomen, Toni
Udgivet 2014

SAPTA: a new design tool for improving TALE nuclease activity

af Lin, Yanni, Fine, Eli J., Zheng, Zhilan, Antico, Christopher J., Voit, Richard A., Porteus, Matthew H., Cradick, Thomas J., Bao, Gang
Udgivet 2014

Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome

af Müller, Maximilian, Lee, Ciaran M, Gasiunas, Giedrius, Davis, Timothy H, Cradick, Thomas J, Siksnys, Virginijus, Bao, Gang, Cathomen, Toni, Mussolino, Claudio
Udgivet i Mol Ther (2016)

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

af Lin, Yanni, Cradick, Thomas J., Brown, Matthew T., Deshmukh, Harshavardhan, Ranjan, Piyush, Sarode, Neha, Wile, Brian M., Vertino, Paula M., Stewart, Frank J., Bao, Gang
Udgivet 2014

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

af Ramirez, Cherie L., Certo, Michael T., Mussolino, Claudio, Goodwin, Mathew J., Cradick, Thomas J., McCaffrey, Anton P., Cathomen, Toni, Scharenberg, Andrew M., Joung, J. Keith
Udgivet 2012

Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection

af Ye, Lin, Wang, Jiaming, Beyer, Ashley I., Teque, Fernando, Cradick, Thomas J., Qi, Zhongxia, Chang, Judy C., Bao, Gang, Muench, Marcus O., Yu, Jingwei, Levy, Jay A., Kan, Yuet Wai
Udgivet 2014

DNA targeting specificity of RNA-guided Cas9 nucleases

af Hsu, Patrick D, Scott, David A, Weinstein, Joshua A, Ran, F Ann, Konermann, Silvana, Agarwala, Vineeta, Li, Yinqing, Fine, Eli J, Wu, Xuebing, Shalem, Ophir, Cradick, Thomas J, Marraffini, Luciano A, Bao, Gang, Zhang, Feng
Udgivet 2013

TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs

af Suzuki, Shingo, Sargent, R Geoffrey, Illek, Beate, Fischer, Horst, Esmaeili-Shandiz, Alaleh, Yezzi, Michael J, Lee, Albert, Yang, Yanu, Kim, Soya, Renz, Peter, Qi, Zhongxia, Yu, Jingwei, Muench, Marcus O, Beyer, Ashley I, Guimarães, Alessander O, Ye, Lin, Chang, Judy, Fine, Eli J, Cradick, Thomas J, Bao, Gang, Rahdar, Meghdad, Porteus, Matthew H, Shuto, Tsuyoshi, Kai, Hirofumi, Kan, Yuet W, Gruenert, Dieter C
Udgivet i Mol Ther Nucleic Acids (2016)