SCY-078 Demonstrates Significant Tissue Penetration in Rats and Mice Following Oral or IV Administration

Por Barat, Stephen, Borroto-Esoda, Katyna, Angulo, David
Publicado no Open Forum Infect Dis (2017)

Assessment of the In Vitro Antifungal Activity of SCY-078 Against a Collection of C. parapsilosis Clinical Isolates

Por Barat, Stephen, Angulo, David, Borroto-Esoda, Katyna, Ghannoum, Mahmoud
Publicado no Open Forum Infect Dis (2017)

In Vitro Combination of Amdoxovir and the Inosine Monophosphate Dehydrogenase Inhibitors Mycophenolic Acid and Ribavirin Demonstrates Potent Activity against Wild-Type and Drug-Res...

Por Borroto-Esoda, Katyna, Myrick, Florence, Feng, Joy, Jeffrey, Jerry, Furman, Phillip
Publicado em 2004

SCY-078 Demonstrates Significant Antifungal Activity in a Murine Model of Invasive Aspergillosis

Por Borroto-Esoda, Katyna, Barat, Stephen, Angulo, David, Holden, Kirsty, Warn, Peter
Publicado no Open Forum Infect Dis (2017)

Antifungal Activity of SCY-078 and Standard Antifungal Agents against 178 Clinical Isolates of Resistant and Susceptible Candida Species

Por Schell, Wiley A., Jones, A. M., Borroto-Esoda, Katyna, Alexander, Barbara D.
Publicado no Antimicrob Agents Chemother (2017)

SCY-078 Is Fungicidal against Candida Species in Time-Kill Studies

Por Scorneaux, Bernard, Angulo, David, Borroto-Esoda, Katyna, Ghannoum, Mahmoud, Peel, Michael, Wring, Stephen
Publicado no Antimicrob Agents Chemother (2017)

De Novo Acquisition of Resistance to SCY-078 in Candida glabrata Involves FKS Mutations That both Overlap and Are Distinct from Those Conferring Echinocandin Resistance

Por Jiménez-Ortigosa, Cristina, Perez, Winder B., Angulo, David, Borroto-Esoda, Katyna, Perlin, David S.
Publicado no Antimicrob Agents Chemother (2017)

Differential Activity of the Oral Glucan Synthase Inhibitor SCY-078 against Wild-Type and Echinocandin-Resistant Strains of Candida Species

Por Pfaller, Michael A., Messer, Shawn A., Rhomberg, Paul R., Borroto-Esoda, Katyna, Castanheira, Mariana
Publicado no Antimicrob Agents Chemother (2017)

MultiCode-RTx Real-Time PCR System for Detection of Subpopulations of K65R Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutant Viruses in Clinical Samples

Por Svarovskaia, Evguenia S., Moser, Michael J., Bae, Andrew S., Prudent, James R., Miller, Michael D., Borroto-Esoda, Katyna
Publicado em 2006

In Vitro Drug Susceptibility Analysis of Hepatitis B Virus Clinical Quasispecies Populations

Por Zhu, Yuao, Curtis, Maria, Snow-Lampart, Andrea, Yang, Huiling, Delaney, William, Miller, Michael D., Borroto-Esoda, Katyna
Publicado em 2007

The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study

Por Feng, Joy Y, Ly, John K, Myrick, Florence, Goodman, Derrick, White, Kirsten L, Svarovskaia, Evguenia S, Borroto-Esoda, Katyna, Miller, Michael D
Publicado em 2009

A classification model for G-to-A hypermutation in hepatitis B virus ultra-deep pyrosequencing reads

Por Reuman, Elizabeth C., Margeridon-Thermet, Severine, Caudill, Harrison B., Liu, Tommy, Borroto-Esoda, Katyna, Svarovskaia, Evguenia S., Holmes, Susan P., Shafer, Robert W.
Publicado em 2010

Low-Level Persistence of Drug Resistance Mutations in Hepatitis B Virus-Infected Subjects with a Past History of Lamivudine Treatment

Por Margeridon-Thermet, Severine, Svarovskaia, Evguenia S., Babrzadeh, Farbod, Martin, Ross, Liu, Tommy F., Pacold, Mary, Reuman, Elizabeth C., Holmes, Susan P., Borroto-Esoda, Katyna, Shafer, Robert W.
Publicado em 2013

The Emerging Pathogen Candida auris: Growth Phenotype, Virulence Factors, Activity of Antifungals, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology a...

Por Larkin, Emily, Hager, Christopher, Chandra, Jyotsna, Mukherjee, Pranab K., Retuerto, Mauricio, Salem, Iman, Long, Lisa, Isham, Nancy, Kovanda, Laura, Borroto-Esoda, Katyna, Wring, Steve, Angulo, David, Ghannoum, Mahmoud
Publicado no Antimicrob Agents Chemother (2017)

Preclinical Pharmacokinetics and Pharmacodynamic Target of SCY-078, a First-in-Class Orally Active Antifungal Glucan Synthesis Inhibitor, in Murine Models of Disseminated Candidias...

Por Wring, Stephen A., Randolph, Ryan, Park, SeongHee, Abruzzo, George, Chen, Qing, Flattery, Amy, Garrett, Graig, Peel, Michael, Outcalt, Russell, Powell, Kendall, Trucksis, Michelle, Angulo, David, Borroto-Esoda, Katyna
Publicado no Antimicrob Agents Chemother (2017)

Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NT...

Por Watashi, Koichi, Sluder, Ann, Daito, Takuji, Matsunaga, Satoko, Ryo, Akihide, Nagamori, Shushi, Iwamoto, Masashi, Nakajima, Syo, Tsukuda, Senko, Borroto‐Esoda, Katyna, Sugiyama, Masaya, Tanaka, Yasuhito, Kanai, Yoshikatsu, Kusuhara, Hiroyuki, Mizokami, Masashi, Wakita, Takaji
Publicado no Hepatology (2014)

Mechanism of Action of 1-β-d-2,6-Diaminopurine Dioxolane, a Prodrug of the Human Immunodeficiency Virus Type 1 Inhibitor 1-β-d-Dioxolane Guanosine

Por Furman, Phillip A., Jeffrey, Jerry, Kiefer, Laura L., Feng, Joy Y., Anderson, Karen S., Borroto-Esoda, Katyna, Hill, Edgar, Copeland, William C., Chu, Chung K., Sommadossi, Jean-Pierre, Liberman, Irina, Schinazi, Raymond F., Painter, George R.
Publicado em 2001