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SCY-078 Demonstrates Significant Tissue Penetration in Rats and Mice Following Oral or IV Administration

BACKGROUND: The ability of a pharmacologic agent to reach target organ(s) in therapeutically-meaningful concentrations is one of the fundamental considerations when developing effective, anti-infective treatments. SCY-078 is a novel, oral and intravenous (IV), triterpenoid glucan synthase inhibitor...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Barat, Stephen, Borroto-Esoda, Katyna, Angulo, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631121/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1204
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