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SCY-078 Demonstrates Significant Tissue Penetration in Rats and Mice Following Oral or IV Administration
BACKGROUND: The ability of a pharmacologic agent to reach target organ(s) in therapeutically-meaningful concentrations is one of the fundamental considerations when developing effective, anti-infective treatments. SCY-078 is a novel, oral and intravenous (IV), triterpenoid glucan synthase inhibitor...
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| Udgivet i: | Open Forum Infect Dis |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5631121/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1204 |
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