SCY-078 Is Fungicidal against Candida Species in Time-Kill Studies

SCY-078 is an orally bioavailable ß-1,3-glucan synthesis inhibitor (GSI) and the first-in-class of structurally novel triterpene antifungals in clinical development for treating candidemia and invasive candidiasis. In vitro susceptibilities by broth microdilution, antifungal carryover, and time-kill...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Scorneaux, Bernard, Angulo, David, Borroto-Esoda, Katyna, Ghannoum, Mahmoud, Peel, Michael, Wring, Stephen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328566/
https://ncbi.nlm.nih.gov/pubmed/28069658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01961-16
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