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A classification model for G-to-A hypermutation in hepatitis B virus ultra-deep pyrosequencing reads
Motivation: G → A hypermutation is an innate antiviral defense mechanism, mediated by host enzymes, which leads to the mutational impairment of viruses. Sensitive and specific identification of host-mediated G → A hypermutation is a novel sequence analysis challenge, particularly for viral deep sequ...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2982158/ https://ncbi.nlm.nih.gov/pubmed/20937597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq570 |
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