Ultra-Deep Pyrosequencing of Hepatitis B Virus Quasispecies from Nucleoside and Nucleotide Reverse-Transcriptase Inhibitor (NRTI)–Treated Patients and NRTI-Naive Patients

The dynamics of emerging nucleoside and nucleotide reverse-transcriptase inhibitor (NRTI) resistance in hepatitis B virus (HBV) are not well understood because standard dideoxynucleotide direct polymerase chain reaction (PCR) sequencing assays detect drug-resistance mutations only after they have be...

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Detalhes bibliográficos
Main Authors: Margeridon-Thermet, Severine, Shulman, Nancy S., Ahmed, Aijaz, Shahriar, Rajin, Liu, Tommy, Wang, Chunlin, Holmes, Susan P., Babrzadeh, Farbod, Gharizadeh, Baback, Hanczaruk, Bozena, Simen, Birgitte B., Egholm, Michael, Shafer, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353721/
https://ncbi.nlm.nih.gov/pubmed/19301976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/597808
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