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Characterization of mutation spectra with ultra-deep pyrosequencing: Application to HIV-1 drug resistance
The detection of mutant spectra within a population of microorganisms is critical for the management of drug-resistant infections. We performed ultra-deep pyrosequencing to detect minor sequence variants in HIV-1 protease and reverse transcriptase (RT) genes from clinical plasma samples. We estimate...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1933516/ https://ncbi.nlm.nih.gov/pubmed/17600086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6468307 |
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