Characterization of mutation spectra with ultra-deep pyrosequencing: Application to HIV-1 drug resistance

The detection of mutant spectra within a population of microorganisms is critical for the management of drug-resistant infections. We performed ultra-deep pyrosequencing to detect minor sequence variants in HIV-1 protease and reverse transcriptase (RT) genes from clinical plasma samples. We estimate...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Chunlin, Mitsuya, Yumi, Gharizadeh, Baback, Ronaghi, Mostafa, Shafer, Robert W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2007
Aiheet:
Methods
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933516/
https://ncbi.nlm.nih.gov/pubmed/17600086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6468307
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