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Viral Population Estimation Using Pyrosequencing
The diversity of virus populations within single infected hosts presents a major difficulty for the natural immune response as well as for vaccine design and antiviral drug therapy. Recently developed pyrophosphate-based sequencing technologies (pyrosequencing) can be used for quantifying this diver...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323617/ https://ncbi.nlm.nih.gov/pubmed/18437230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000074 |
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