A classification model for G-to-A hypermutation in hepatitis B virus ultra-deep pyrosequencing reads

Motivation: G → A hypermutation is an innate antiviral defense mechanism, mediated by host enzymes, which leads to the mutational impairment of viruses. Sensitive and specific identification of host-mediated G → A hypermutation is a novel sequence analysis challenge, particularly for viral deep sequ...

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Bibliografiske detaljer
Main Authors: Reuman, Elizabeth C., Margeridon-Thermet, Severine, Caudill, Harrison B., Liu, Tommy, Borroto-Esoda, Katyna, Svarovskaia, Evguenia S., Holmes, Susan P., Shafer, Robert W.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Discovery Note
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982158/
https://ncbi.nlm.nih.gov/pubmed/20937597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq570
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