RNA-Dependent DNA Polymerase Activity in Preparations of a Mutant of Newcastle Disease Virus Arising from Persistently Infected L Cells

Por Furman, Phillip A., Hallum, Jules V.
Publicado em 1973

Effect of Acyclovir on Viral Protein Synthesis in Cells Infected with Herpes Simplex Virus Type 1

Por Furman, Phillip A., McGuirt, Paul V.
Publicado em 1983

Rebound of Hepatitis B Virus Replication in HepG2 Cells after Cessation of Antiviral Treatment

Por Abdelhamed, Ayman M., Kelley, Colleen M., Miller, Thomas G., Furman, Phillip A., Isom, Harriet C.
Publicado em 2002

Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine

Por Elion, Gertrude B., Furman, Phillip A., Fyfe, James A., Miranda, Paulo de, Beauchamp, Lilia, Schaeffer, Howard J.
Publicado em 1977

Comparison of Anti-Hepatitis B Virus Activities of Lamivudine and Clevudine by a Quantitative Assay

Por Abdelhamed, Ayman M., Kelley, Colleen M., Miller, Thomas G., Furman, Phillip A., Cable, Edward E., Isom, Harriet C.
Publicado em 2003

Hepatitis C Virus Nucleotide Inhibitors PSI-352938 and PSI-353661 Exhibit a Novel Mechanism of Resistance Requiring Multiple Mutations within Replicon RNA

Por Lam, Angela M., Espiritu, Christine, Bansal, Shalini, Micolochick Steuer, Holly M., Zennou, Veronique, Otto, Michael J., Furman, Phillip A.
Publicado em 2011

Relationship between Antiviral Activity and Host Toxicity: Comparison of the Incorporation Efficiencies of 2′,3′-Dideoxy-5-Fluoro-3′-Thiacytidine-Triphosphate Analogs by Human Immu...

Por Feng, Joy Y., Murakami, Eisuke, Zorca, Suzana M., Johnson, Allison A., Johnson, Kenneth A., Schinazi, Raymond F., Furman, Phillip A., Anderson, Karen S.
Publicado em 2004

Kinetics of Hepadnavirus Loss from the Liver during Inhibition of Viral DNA Synthesis

Por Zhu, Yuao, Yamamoto, Toshiki, Cullen, John, Saputelli, Jeffry, Aldrich, Carol E., Miller, Darren S., Litwin, Samuel, Furman, Phillip A., Jilbert, Allison R., Mason, William S.
Publicado em 2001

The Mechanism of Action of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methylcytidine Involves a Second Metabolic Pathway Leading to β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyluridine 5′-Triphosphate, a Po...

Por Murakami, Eisuke, Niu, Congrong, Bao, Haiying, Micolochick Steuer, Holly M., Whitaker, Tony, Nachman, Tammy, Sofia, Michael A., Wang, Peiyuan, Otto, Michael J., Furman, Phillip A.
Publicado em 2008

Molecular and Structural Basis for the Roles of Hepatitis C Virus Polymerase NS5B Amino Acids 15, 223, and 321 in Viral Replication and Drug Resistance

Por Lam, Angela M., Edwards, Thomas E., Mosley, Ralph T., Murakami, Eisuke, Bansal, Shalini, Lugo, Christopher, Bao, Haiying, Otto, Michael J., Sofia, Michael J., Furman, Phillip A.
Publicado no Antimicrob Agents Chemother (2014)

Genotype and Subtype Profiling of PSI-7977 as a Nucleotide Inhibitor of Hepatitis C Virus

Por Lam, Angela M., Espiritu, Christine, Bansal, Shalini, Micolochick Steuer, Holly M., Niu, Congrong, Zennou, Veronique, Keilman, Meg, Zhu, Yuao, Lan, Shuiyun, Otto, Michael J., Furman, Phillip A.
Publicado em 2012

Mechanism of Activation of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

Por Murakami, Eisuke, Bao, Haiying, Ramesh, Mangala, McBrayer, Tamara R., Whitaker, Tony, Micolochick Steuer, Holly M., Schinazi, Raymond F., Stuyver, Lieven J., Obikhod, Aleksandr, Otto, Michael J., Furman, Phillip A.
Publicado em 2007

Mechanism of Activation of PSI-7851 and Its Diastereoisomer PSI-7977

Por Murakami, Eisuke, Tolstykh, Tatiana, Bao, Haiying, Niu, Congrong, Steuer, Holly M. Micolochick, Bao, Donghui, Chang, Wonsuk, Espiritu, Christine, Bansal, Shalini, Lam, Angela M., Otto, Michael J., Sofia, Michael J., Furman, Phillip A.
Publicado em 2010

Mechanism of Action of 1-β-d-2,6-Diaminopurine Dioxolane, a Prodrug of the Human Immunodeficiency Virus Type 1 Inhibitor 1-β-d-Dioxolane Guanosine

Por Furman, Phillip A., Jeffrey, Jerry, Kiefer, Laura L., Feng, Joy Y., Anderson, Karen S., Borroto-Esoda, Katyna, Hill, Edgar, Copeland, William C., Chu, Chung K., Sommadossi, Jean-Pierre, Liberman, Irina, Schinazi, Raymond F., Painter, George R.
Publicado em 2001

Activity and the Metabolic Activation Pathway of the Potent and Selective Hepatitis C Virus Pronucleotide Inhibitor PSI-353661

Por Furman, Phillip A., Murakami, Eisuke, Niu, Congrong, Lam, Angela M., Espiritu, Christine, Bansal, Shalini, Bao, Haiying, Tolstykh, Tatiana, Steuer, Holly Micolochick, Keilman, Meg, Zennou, Veronique, Bourne, Nigel, Veselenak, Ronald L., Chang, Wonsuk, Ross, Bruce S., Du, Jinfa, Otto, Michael J., Sofia, Michael J.
Publicado em 2011

Inhibition of Hepatitis C Virus Replicon RNA Synthesis by PSI-352938, a Cyclic Phosphate Prodrug of β-d-2′-Deoxy-2′-α-Fluoro-2′-β-C-Methylguanosine

Por Lam, Angela M., Espiritu, Christine, Murakami, Eisuke, Zennou, Veronique, Bansal, Shalini, Micolochick Steuer, Holly M., Niu, Congrong, Keilman, Meg, Bao, Haiying, Bourne, Nigel, Veselenak, Ronald L., Reddy, P. Ganapati, Chang, Wonsuk, Du, Jinfa, Nagarathnam, Dhanapalan, Sofia, Michael J., Otto, Michael J., Furman, Phillip A.
Publicado em 2011

Discovery of PSI-353661, a Novel Purine Nucleotide Prodrug for the Treatment of HCV Infection

Por Chang, Wonsuk, Bao, Donghui, Chun, Byoung-Kwon, Naduthambi, Devan, Nagarathnam, Dhanapalan, Rachakonda, Suguna, Reddy, P. Ganapati, Ross, Bruce S., Zhang, Hai-Ren, Bansal, Shalini, Espiritu, Christine L., Keilman, Meg, Lam, Angela M., Niu, Congrong, Steuer, Holly Micolochick, Furman, Phillip A., Otto, Michael J., Sofia, Michael J.
Publicado em 2010

Metabolic Activation of the Anti-Hepatitis C Virus Nucleotide Prodrug PSI-352938

Por Niu, Congrong, Tolstykh, Tatiana, Bao, Haiying, Park, Yeojin, Babusis, Darius, Lam, Angela M., Bansal, Shalini, Du, Jinfa, Chang, Wonsuk, Reddy, P. Ganapati, Zhang, Hai-Ren, Woolley, Joseph, Wang, Li-Quan, Chao, Piyun B., Ray, Adrian S., Otto, Michael J., Sofia, Michael J., Furman, Phillip A., Murakami, Eisuke
Publicado em 2012

PSI-7851, a Pronucleotide of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication

Por Lam, Angela M., Murakami, Eisuke, Espiritu, Christine, Steuer, Holly M. Micolochick, Niu, Congrong, Keilman, Meg, Bao, Haiying, Zennou, Veronique, Bourne, Nigel, Julander, Justin G., Morrey, John D., Smee, Donald F., Frick, David N., Heck, Julie A., Wang, Peiyuan, Nagarathnam, Dhanapalan, Ross, Bruce S., Sofia, Michael J., Otto, Michael J., Furman, Phillip A.
Publicado em 2010