Genotype and Subtype Profiling of PSI-7977 as a Nucleotide Inhibitor of Hepatitis C Virus

PSI-7977, a prodrug of 2′-F-2′-C-methyluridine monophosphate, is the purified diastereoisomer of PSI-7851 and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. In this study, we profiled the activity of PSI-7977 and its ability to select for resistance usin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lam, Angela M., Espiritu, Christine, Bansal, Shalini, Micolochick Steuer, Holly M., Niu, Congrong, Zennou, Veronique, Keilman, Meg, Zhu, Yuao, Lan, Shuiyun, Otto, Michael J., Furman, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370800/
https://ncbi.nlm.nih.gov/pubmed/22430955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00054-12
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados