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Kinetics of Hepadnavirus Loss from the Liver during Inhibition of Viral DNA Synthesis

Hepadnaviruses replicate by reverse transcription, which takes place in the cytoplasm of the infected hepatocyte. Viral RNAs, including the pregenome, are transcribed from a covalently closed circular (ccc) viral DNA that is found in the nucleus. Inhibitors of the viral reverse transcriptase can blo...

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Detalhes bibliográficos
Main Authors: Zhu, Yuao, Yamamoto, Toshiki, Cullen, John, Saputelli, Jeffry, Aldrich, Carol E., Miller, Darren S., Litwin, Samuel, Furman, Phillip A., Jilbert, Allison R., Mason, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113925/
https://ncbi.nlm.nih.gov/pubmed/11119601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.1.311-322.2001
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