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Kinetics of Hepadnavirus Loss from the Liver during Inhibition of Viral DNA Synthesis

Hepadnaviruses replicate by reverse transcription, which takes place in the cytoplasm of the infected hepatocyte. Viral RNAs, including the pregenome, are transcribed from a covalently closed circular (ccc) viral DNA that is found in the nucleus. Inhibitors of the viral reverse transcriptase can blo...

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Published in:J Virol
Main Authors: Zhu, Yuao, Yamamoto, Toshiki, Cullen, John, Saputelli, Jeffry, Aldrich, Carol E., Miller, Darren S., Litwin, Samuel, Furman, Phillip A., Jilbert, Allison R., Mason, William S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2001
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113925/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11119601/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.1.311-322.2001
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