Molecular and Structural Basis for the Roles of Hepatitis C Virus Polymerase NS5B Amino Acids 15, 223, and 321 in Viral Replication and Drug Resistance

Podobne zapisy

• Mechanism of Activation of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase
  od: Murakami, Eisuke, i wsp.
  Wydane: (2007)
• The Mechanism of Action of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methylcytidine Involves a Second Metabolic Pathway Leading to β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyluridine 5′-Triphosphate, a Potent Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase
  od: Murakami, Eisuke, i wsp.
  Wydane: (2008)
• Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA
  od: Mosley, Ralph T., i wsp.
  Wydane: (2012)
• Inhibition of Hepatitis C Virus Replicon RNA Synthesis by PSI-352938, a Cyclic Phosphate Prodrug of β-d-2′-Deoxy-2′-α-Fluoro-2′-β-C-Methylguanosine
  od: Lam, Angela M., i wsp.
  Wydane: (2011)
• Metabolic Activation of the Anti-Hepatitis C Virus Nucleotide Prodrug PSI-352938
  od: Niu, Congrong, i wsp.
  Wydane: (2012)