Dose Range Evaluation of Liposomal Nystatin and Comparisons with Amphotericin B and Amphotericin B Lipid Complex in Temporarily Neutropenic Mice Infected with an Isolate of Aspergi...

Por Denning, David W., Warn, Peter
Publicado em 1999

SMT19969 for Clostridium difficile infection (CDI): in vivo efficacy compared with fidaxomicin and vancomycin in the hamster model of CDI

Por Sattar, Abdul, Thommes, Pia, Payne, Lloyd, Warn, Peter, Vickers, Richard J.
Publicado no J Antimicrob Chemother (2015)

A single dose of epidermicin NI01 is sufficient to eradicate MRSA from the nares of cotton rats

Por Halliwell, Samantha, Warn, Peter, Sattar, Abdul, Derrick, Jeremy P., Upton, Mathew
Publicado no J Antimicrob Chemother (2017)

Detection of Aspergillus fumigatus in a Rat Model of Invasive Pulmonary Aspergillosis by Real-Time Nucleic Acid Sequence-Based Amplification

Por Zhao, Yanan, Park, Steven, Warn, Peter, Shrief, Raghdaa, Harrison, Elizabeth, Perlin, David S.
Publicado em 2010

Pharmacokinetics and Pharmacodynamics of a Novel Triazole, Isavuconazole: Mathematical Modeling, Importance of Tissue Concentrations, and Impact of Immune Status on Antifungal Effe...

Por Warn, Peter A., Sharp, Andrew, Parmar, Arvind, Majithiya, Jayesh, Denning, David W., Hope, William W.
Publicado em 2009

Peroral Amphotericin B Polymer Nanoparticles Lead to Comparable or Superior In Vivo Antifungal Activity to That of Intravenous Ambisome(®) or Fungizone™

Por Italia, Jagdishbhai L., Sharp, Andrew, Carter, Katharine C., Warn, Peter, Kumar, M. N. V. Ravi
Publicado em 2011

Combination of Voriconazole and Anidulafungin for Treatment of Triazole-Resistant Aspergillus fumigatus in an In Vitro Model of Invasive Pulmonary Aspergillosis

Por Jeans, Adam R., Howard, Susan J., Al-Nakeeb, Zaid, Goodwin, Joanne, Gregson, Lea, Warn, Peter A., Hope, William W.
Publicado em 2012

Interrogation of Related Clinical Pan-Azole-Resistant Aspergillus fumigatus Strains: G138C, Y431C, and G434C Single Nucleotide Polymorphisms in cyp51A, Upregulation of cyp51A, and...

Por Albarrag, Ahmed M., Anderson, Michael J., Howard, Susan J., Robson, Geoff D., Warn, Peter A., Sanglard, Dominique, Denning, David W.
Publicado em 2011

Disease Progression and Resolution in Rodent Models of Clostridium difficile Infection and Impact of Antitoxin Antibodies and Vancomycin

Por Warn, Peter, Thommes, Pia, Sattar, Abdul, Corbett, David, Flattery, Amy, Zhang, Zuo, Black, Todd, Hernandez, Lorraine D., Therien, Alex G.
Publicado no Antimicrob Agents Chemother (2016)

Effect of Neutropenia and Treatment Delay on the Response to Antifungal Agents in Experimental Disseminated Candidiasis

Por Hope, William W., Drusano, George L., Moore, Caroline B., Sharp, Andrew, Louie, Arnold, Walsh, Thomas J., Denning, David W., Warn, Peter A.
Publicado em 2007

Pharmacodynamics of Echinocandins against Candida glabrata: Requirement for Dosage Escalation To Achieve Maximal Antifungal Activity in Neutropenic Hosts

Por Howard, Susan J., Livermore, Joanne, Sharp, Andrew, Goodwin, Joanne, Gregson, Lea, Alastruey-Izquierdo, A., Perlin, D. S., Warn, Peter A., Hope, William W.
Publicado em 2011

Derivation of an In Vivo Drug Exposure Breakpoint for Flucytosine against Candida albicans and Impact of the MIC, Growth Rate, and Resistance Genotype on the Antifungal Effect

Por Hope, William W., Warn, Peter A., Sharp, Andrew, Howard, Susan, Kasai, Miki, Louie, Arnold, Walsh, Thomas J., Drusano, George L., Denning, David W.
Publicado em 2006

Optimization of the Dosage of Flucytosine in Combination with Amphotericin B for Disseminated Candidiasis: a Pharmacodynamic Rationale for Reduced Dosing

Por Hope, William W., Warn, Peter A., Sharp, Andrew, Reed, Paul, Keevil, Brian, Louie, Arnold, Walsh, Thomas J., Denning, David W., Drusano, George L.
Publicado em 2007

Pharmacokinetics and Pharmacodynamics of Posaconazole for Invasive Pulmonary Aspergillosis: Clinical Implications for Antifungal Therapy

Por Howard, Susan J., Lestner, Jodi M., Sharp, Andrew, Gregson, Lea, Goodwin, Joanne, Slater, Joanne, Majithiya, Jayesh B., Warn, Peter A., Hope, William W.
Publicado em 2011

Azole Resistance of Aspergillus fumigatus Biofilms Is Partly Associated with Efflux Pump Activity

Por Rajendran, Ranjith, Mowat, Eilidh, McCulloch, Elaine, Lappin, David F., Jones, Brian, Lang, Sue, Majithiya, Jayesh B., Warn, Peter, Williams, Craig, Ramage, Gordon
Publicado em 2011

The Aspergillus fumigatus Dihydroxyacid Dehydratase Ilv3A/IlvC Is Required for Full Virulence

Por Oliver, Jason D., Kaye, Sarah J., Tuckwell, Danny, Johns, Anna E., Macdonald, Darel A., Livermore, Joanne, Warn, Peter A., Birch, Mike, Bromley, Michael J.
Publicado em 2012

Pharmacodynamics of Itraconazole against Aspergillus fumigatus in an In Vitro Model of the Human Alveolus: Perspectives on the Treatment of Triazole-Resistant Infection and Utility...

Por Al-Nakeeb, Zaid, Sudan, Ajay, Jeans, Adam R., Gregson, Lea, Goodwin, Joanne, Warn, Peter A., Felton, Timothy W., Howard, Susan J., Hope, William W.
Publicado em 2012

Statistical Analyses of Correlation between Fluconazole MICs for Candida spp. Assessed by Standard Methods Set Forth by the European Committee on Antimicrobial Susceptibility Testi...

Por Rodriguez-Tudela, Juan Luis, Donnelly, J. Peter, Pfaller, Michael A., Chryssantou, Erja, Warn, Peter, Denning, David W., Espinel-Ingroff, Ana, Barchiesi, Francesco, Cuenca-Estrella, Manuel
Publicado em 2007

Inactivation of Transcription Factor Gene ACE2 in the Fungal Pathogen Candida glabrata Results in Hypervirulence

Por Kamran, Mohammed, Calcagno, Ana-Maria, Findon, Helen, Bignell, Elaine, Jones, Michael D., Warn, Peter, Hopkins, Philip, Denning, David W., Butler, Geraldine, Rogers, Thomas, Mühlschlegel, Fritz A., Haynes, Ken
Publicado em 2004

Pharmacokinetics and Pharmacodynamics of Fluconazole for Cryptococcal Meningoencephalitis: Implications for Antifungal Therapy and In Vitro Susceptibility Breakpoints

Por Sudan, Ajay, Livermore, Joanne, Howard, Susan J., Al-Nakeeb, Zaid, Sharp, Andrew, Goodwin, Joanne, Gregson, Lea, Warn, Peter A., Felton, Tim W., Perfect, John R., Harrison, Thomas S., Hope, William W.
Publicado em 2013