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Pharmacokinetics and Pharmacodynamics of Posaconazole for Invasive Pulmonary Aspergillosis: Clinical Implications for Antifungal Therapy

Background. Posaconazole is a triazole with anti-Aspergillus activity. However, little is known about the utility of posaconazole as primary therapy for invasive pulmonary aspergillosis. Methods. An in vitro model of the human alveolus was used to study the impact of minimum inhibitory concentration...

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Autors principals: Howard, Susan J., Lestner, Jodi M., Sharp, Andrew, Gregson, Lea, Goodwin, Joanne, Slater, Joanne, Majithiya, Jayesh B., Warn, Peter A., Hope, William W.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069735/
https://ncbi.nlm.nih.gov/pubmed/21357943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir023
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