Pharmacokinetics and Pharmacodynamics of Posaconazole for Invasive Pulmonary Aspergillosis: Clinical Implications for Antifungal Therapy

Background. Posaconazole is a triazole with anti-Aspergillus activity. However, little is known about the utility of posaconazole as primary therapy for invasive pulmonary aspergillosis. Methods. An in vitro model of the human alveolus was used to study the impact of minimum inhibitory concentration...

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Main Authors: Howard, Susan J., Lestner, Jodi M., Sharp, Andrew, Gregson, Lea, Goodwin, Joanne, Slater, Joanne, Majithiya, Jayesh B., Warn, Peter A., Hope, William W.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Major Articles and Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069735/
https://ncbi.nlm.nih.gov/pubmed/21357943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir023
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