Pharmacodynamics of Itraconazole against Aspergillus fumigatus in an In Vitro Model of the Human Alveolus: Perspectives on the Treatment of Triazole-Resistant Infection and Utility of Airway Administration

Itraconazole is used for the prevention and treatment of infections caused by Aspergillus fumigatus. An understanding of the pharmacodynamics of itraconazole against wild-type and triazole-resistant strains provides a basis for innovative therapeutic strategies for treatment of infections. An in vit...

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Main Authors: Al-Nakeeb, Zaid, Sudan, Ajay, Jeans, Adam R., Gregson, Lea, Goodwin, Joanne, Warn, Peter A., Felton, Timothy W., Howard, Susan J., Hope, William W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421583/
https://ncbi.nlm.nih.gov/pubmed/22615280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00141-12
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