Itraconazole resistance in Aspergillus fumigatus.

Invasive aspergillosis is an increasingly frequent opportunistic infection in immunocompromised patients. Only two agents, amphotericin B and itraconazole, are licensed for therapy. Itraconazole acts through inhibition of a P-450 enzyme undertaking sterol 14alpha demethylation. In vitro resistance i...

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Hlavní autoři: Denning, D W, Venkateswarlu, K, Oakley, K L, Anderson, M J, Manning, N J, Stevens, D A, Warnock, D W, Kelly, S L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC163916/
https://ncbi.nlm.nih.gov/pubmed/9174200
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