Itraconazole resistance in Aspergillus fumigatus.

Invasive aspergillosis is an increasingly frequent opportunistic infection in immunocompromised patients. Only two agents, amphotericin B and itraconazole, are licensed for therapy. Itraconazole acts through inhibition of a P-450 enzyme undertaking sterol 14alpha demethylation. In vitro resistance i...

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Библиографические подробности

Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	Denning, D W, Venkateswarlu, K, Oakley, K L, Anderson, M J, Manning, N J, Stevens, D A, Warnock, D W, Kelly, S L
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1997
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163916/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9174200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.6.1364
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