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Efficacy of SCH56592 in a Rabbit Model of Invasive Aspergillosis

SCH56592 (SCH) was evaluated in an immunosuppressed rabbit model of invasive aspergillosis. SCH was more effective than similar doses of itraconazole and as effective as amphotericin B in the clearance of Aspergillus spp. from tissues. Compared with controls, SCH regimens reduced mortality, improved...

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Autors principals: Kirkpatrick, William R., McAtee, Robert K., Fothergill, Annette W., Loebenberg, David, Rinaldi, Michael G., Patterson, Thomas F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC89767/
https://ncbi.nlm.nih.gov/pubmed/10681359
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