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Efficacy of SCH56592 in a Rabbit Model of Invasive Aspergillosis

SCH56592 (SCH) was evaluated in an immunosuppressed rabbit model of invasive aspergillosis. SCH was more effective than similar doses of itraconazole and as effective as amphotericin B in the clearance of Aspergillus spp. from tissues. Compared with controls, SCH regimens reduced mortality, improved...

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Main Authors: Kirkpatrick, William R., McAtee, Robert K., Fothergill, Annette W., Loebenberg, David, Rinaldi, Michael G., Patterson, Thomas F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC89767/
https://ncbi.nlm.nih.gov/pubmed/10681359
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