Efficacy of the Echinocandin Caspofungin against Disseminated Aspergillosis and Candidiasis in Cyclophosphamide-Induced Immunosuppressed Mice

The in vivo efficacy of the echinocandin antifungal caspofungin acetate (caspofungin; MK-0991) was evaluated in models of disseminated aspergillosis and candidiasis in mice with cyclophosphamide (CY)-induced immunosuppression. Caspofungin is a 1,3-β-d-glucan synthesis inhibitor efficacious against a...

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Detalhes bibliográficos
Main Authors: Abruzzo, George K., Gill, Charles J., Flattery, Amy M., Kong, Li, Leighton, Claire, Smith, Jeffrey G., Pikounis, V. Bill, Bartizal, Ken, Rosen, Hugh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90063/
https://ncbi.nlm.nih.gov/pubmed/10952573
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