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Preliminary animal pharmacokinetics of the parenteral antifungal agent MK-0991 (L-743,872).

MK-0991 (L-743,872) is a potent antifungal agent featuring long half-life pharmacokinetics. The pharmacokinetics of MK-0991 administered intravenously to mice, rats, rhesus monkeys, and chimpanzees is presented. Unique to MK-0991 is its consistent cross-species performance. The range of values for t...

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Bibliographische Detailangaben
Hauptverfasser: Hajdu, R, Thompson, R, Sundelof, J G, Pelak, B A, Bouffard, F A, Dropinski, J F, Kropp, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164125/
https://ncbi.nlm.nih.gov/pubmed/9371330
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