Preliminary animal pharmacokinetics of the parenteral antifungal agent MK-0991 (L-743,872).

MK-0991 (L-743,872) is a potent antifungal agent featuring long half-life pharmacokinetics. The pharmacokinetics of MK-0991 administered intravenously to mice, rats, rhesus monkeys, and chimpanzees is presented. Unique to MK-0991 is its consistent cross-species performance. The range of values for t...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Hajdu, R, Thompson, R, Sundelof, J G, Pelak, B A, Bouffard, F A, Dropinski, J F, Kropp, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164125/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.11.2339
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