Efficacy of the Echinocandin Caspofungin against Disseminated Aspergillosis and Candidiasis in Cyclophosphamide-Induced Immunosuppressed Mice

The in vivo efficacy of the echinocandin antifungal caspofungin acetate (caspofungin; MK-0991) was evaluated in models of disseminated aspergillosis and candidiasis in mice with cyclophosphamide (CY)-induced immunosuppression. Caspofungin is a 1,3-β-d-glucan synthesis inhibitor efficacious against a...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Abruzzo, George K., Gill, Charles J., Flattery, Amy M., Kong, Li, Leighton, Claire, Smith, Jeffrey G., Pikounis, V. Bill, Bartizal, Ken, Rosen, Hugh
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90063/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10952573/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.9.2310-2318.2000
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