Efficacy of SCH56592 in a Rabbit Model of Invasive Aspergillosis

SCH56592 (SCH) was evaluated in an immunosuppressed rabbit model of invasive aspergillosis. SCH was more effective than similar doses of itraconazole and as effective as amphotericin B in the clearance of Aspergillus spp. from tissues. Compared with controls, SCH regimens reduced mortality, improved...

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Главные авторы: Kirkpatrick, William R., McAtee, Robert K., Fothergill, Annette W., Loebenberg, David, Rinaldi, Michael G., Patterson, Thomas F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2000
Предметы:
Experimental Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC89767/
https://ncbi.nlm.nih.gov/pubmed/10681359
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