Pathogenic yeasts

Por Ashbee, Ruth., Bignell, Elaine M.
Publicado em 2010

Transcript levels of the Aspergillus fumigatus Cdc42 module, polarisome, and septin genes show little change from dormancy to polarity establishment

Por Oda, Ken, Bignell, Elaine, Kang, S. Earl, Momany, Michelle
Publicado no Med Mycol (2017)

Microbial uptake by the respiratory epithelium: outcomes for host and pathogen

Por Bertuzzi, Margherita, Hayes, Gemma E, Bignell, Elaine M
Publicado no FEMS Microbiol Rev (2019)

A Regulator of Aspergillus fumigatus Extracellular Proteolytic Activity Is Dispensable for Virulence

Por Bergmann, Anna, Hartmann, Thomas, Cairns, Timothy, Bignell, Elaine M., Krappmann, Sven
Publicado em 2009

Developing novel antifungals: lessons from G protein-coupled receptors

Por Velazhahan, Vaithish, McCann, Bethany L., Bignell, Elaine, Tate, Christopher G.
Publicado no Trends Pharmacol Sci (2023)

Secondary metabolite arsenal of an opportunistic pathogenic fungus

Por Bignell, Elaine, Cairns, Timothy C., Throckmorton, Kurt, Nierman, William C., Keller, Nancy P.
Publicado no Philos Trans R Soc Lond B Biol Sci (2016)

Different Stress-Induced Calcium Signatures Are Reported by Aequorin-Mediated Calcium Measurements in Living Cells of Aspergillus fumigatus

Por Muñoz, Alberto, Bertuzzi, Margherita, Bettgenhaeuser, Jan, Iakobachvili, Nino, Bignell, Elaine M., Read, Nick D.
Publicado no PLoS One (2015)

Virulence Comparisons of Aspergillus nidulans Mutants Are Confounded by the Inflammatory Response of p47(phox)(−/−) Mice

Por Bignell, Elaine, Negrete-Urtasun, Susana, Calcagno, Ana Maria, Arst, Herbert N., Rogers, Tom, Haynes, Ken
Publicado em 2005

On the lineage of Aspergillus fumigatus isolates in common laboratory use

Por Bertuzzi, Margherita, van Rhijn, Norman, Krappmann, Sven, Bowyer, Paul, Bromley, Michael J, Bignell, Elaine M
Publicado no Med Mycol (2020)

Development of a marker-free mutagenesis system using CRISPR-Cas9 in the pathogenic mould Aspergillus fumigatus

Por van Rhijn, Norman, Furukawa, Takanori, Zhao, Can, McCann, Bethany L., Bignell, Elaine, Bromley, Michael J.
Publicado no Fungal Genet Biol (2020)

Siderophore Biosynthesis But Not Reductive Iron Assimilation Is Essential for Aspergillus fumigatus Virulence

Por Schrettl, Markus, Bignell, Elaine, Kragl, Claudia, Joechl, Chistoph, Rogers, Tom, Arst, Herbert N., Haynes, Ken, Haas, Hubertus
Publicado em 2004

In silico modeling of spore inhalation reveals fungal persistence following low dose exposure

Por Tanaka, Reiko J., Boon, Neville J., Vrcelj, Katarina, Nguyen, Anita, Vinci, Carmelina, Armstrong-James, Darius, Bignell, Elaine
Publicado no Sci Rep (2015)

A new and clinically relevant murine model of solid-organ transplant aspergillosis

Por Herbst, Susanne, Shah, Anand, Carby, Martin, Chusney, Gary, Kikkeri, Naresh, Dorling, Anthony, Bignell, Elaine, Shaunak, Sunil, Armstrong-James, Darius
Publicado em 2013

Anti-Aspergillus Activities of the Respiratory Epithelium in Health and Disease

Por Bertuzzi, Margherita, Hayes, Gemma E., Icheoku, Uju J., van Rhijn, Norman, Denning, David W., Osherov, Nir, Bignell, Elaine M.
Publicado no J Fungi (Basel) (2018)

Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus

Por Gsaller, Fabio, Furukawa, Takanori, Carr, Paul D., Rash, Bharat, Jöchl, Christoph, Bertuzzi, Margherita, Bignell, Elaine M., Bromley, Michael J.
Publicado no Antimicrob Agents Chemother (2018)

A Modified Recombineering Protocol for the Genetic Manipulation of Gene Clusters in Aspergillus fumigatus

Por Alcazar-Fuoli, Laura, Cairns, Timothy, Lopez, Jordi F., Zonja, Bozo, Pérez, Sandra, Barceló, Damià, Igarashi, Yasuhiro, Bowyer, Paul, Bignell, Elaine
Publicado no PLoS One (2014)

Distinct Roles for Intra- and Extracellular Siderophores during Aspergillus fumigatus Infection

Por Schrettl, Markus, Bignell, Elaine, Kragl, Claudia, Sabiha, Yasmin, Loss, Omar, Eisendle, Martin, Wallner, Anja, Arst, Herbert N, Haynes, Ken, Haas, Hubertus
Publicado em 2007

Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus

Por Yasmin, Sabiha, Alcazar-Fuoli, Laura, Gründlinger, Mario, Puempel, Thomas, Cairns, Timothy, Blatzer, Michael, Lopez, Jordi F., Grimalt, Joan O., Bignell, Elaine, Haas, Hubertus
Publicado em 2012

Genetic Bypass of Aspergillus nidulans crzA Function in Calcium Homeostasis

Por Almeida, Ricardo S., Loss, Omar, Colabardini, Ana Cristina, Brown, Neil Andrew, Bignell, Elaine, Savoldi, Marcela, Pantano, Sergio, Goldman, Maria Helena S., Arst, Herbert N., Goldman, Gustavo H.
Publicado em 2013

On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction

Por Espeso, Eduardo A., Roncal, Tomás, Díez, Eliecer, Rainbow, Lynne, Bignell, Elaine, Álvaro, Josué, Suárez, Teresa, Denison, Steven H., Tilburn, Joan, Arst, Herbert N., Peñalva, Miguel A.
Publicado em 2000