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Development of a marker-free mutagenesis system using CRISPR-Cas9 in the pathogenic mould Aspergillus fumigatus

Aspergillus fumigatus is a saprophytic fungal pathogen that is the cause of more than 300,000 life-threatening infections annually. Our understanding of pathogenesis and factors contributing to disease progression are limited. Development of rapid and versatile gene editing methodologies for A. fumi...

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Detalhes bibliográficos
Publicado no:Fungal Genet Biol
Main Authors: van Rhijn, Norman, Furukawa, Takanori, Zhao, Can, McCann, Bethany L., Bignell, Elaine, Bromley, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768092/
https://ncbi.nlm.nih.gov/pubmed/33122116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fgb.2020.103479
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