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Development of the CRISPR/Cas9 System for Targeted Gene Disruption in Aspergillus fumigatus
Low rates of homologous recombination have broadly encumbered genetic studies in the fungal pathogen Aspergillus fumigatus. The CRISPR/Cas9 system of bacteria has recently been developed for targeted mutagenesis of eukaryotic genomes with high efficiency and, importantly, through a mechanism indepen...
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| Publié dans: | Eukaryot Cell |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621320/ https://ncbi.nlm.nih.gov/pubmed/26318395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00107-15 |
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