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Development of the CRISPR/Cas9 System for Targeted Gene Disruption in Aspergillus fumigatus

Low rates of homologous recombination have broadly encumbered genetic studies in the fungal pathogen Aspergillus fumigatus. The CRISPR/Cas9 system of bacteria has recently been developed for targeted mutagenesis of eukaryotic genomes with high efficiency and, importantly, through a mechanism indepen...

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Pubblicato in:Eukaryot Cell
Autori principali: Fuller, Kevin K., Chen, Shan, Loros, Jennifer J., Dunlap, Jay C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621320/
https://ncbi.nlm.nih.gov/pubmed/26318395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00107-15
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