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Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus
The antifungal drug 5-flucytosine (5FC), a derivative of the nucleobase cytosine, is licensed for the treatment of fungal diseases; however, it is rarely used as a monotherapeutic to treat Aspergillus infection. Despite being potent against other fungal pathogens, 5FC has limited activity against As...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5971587/ https://ncbi.nlm.nih.gov/pubmed/29610197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02593-17 |
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