Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus

Aspergillus fumigatus is the most common airborne fungal pathogen for humans. In this mold, iron starvation induces production of the siderophore triacetylfusarinine C (TAFC). Here we demonstrate a link between TAFC and ergosterol biosynthetic pathways, which are both critical for virulence and trea...

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Detalhes bibliográficos
Main Authors: Yasmin, Sabiha, Alcazar-Fuoli, Laura, Gründlinger, Mario, Puempel, Thomas, Cairns, Timothy, Blatzer, Michael, Lopez, Jordi F., Grimalt, Joan O., Bignell, Elaine, Haas, Hubertus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286978/
https://ncbi.nlm.nih.gov/pubmed/22106303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106399108
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