On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction

In response to alkaline ambient pH, the Aspergillus nidulans PacC transcription factor mediating pH regulation of gene expression is activated by proteolytic removal of a negative-acting C–terminal domain. We demonstrate interactions involving the ∼150 C–terminal PacC residues and two regions locate...

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Hauptverfasser: Espeso, Eduardo A., Roncal, Tomás, Díez, Eliecer, Rainbow, Lynne, Bignell, Elaine, Álvaro, Josué, Suárez, Teresa, Denison, Steven H., Tilburn, Joan, Arst, Herbert N., Peñalva, Miguel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC305610/
https://ncbi.nlm.nih.gov/pubmed/10675341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.719
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