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On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction
In response to alkaline ambient pH, the Aspergillus nidulans PacC transcription factor mediating pH regulation of gene expression is activated by proteolytic removal of a negative-acting C–terminal domain. We demonstrate interactions involving the ∼150 C–terminal PacC residues and two regions locate...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305610/ https://ncbi.nlm.nih.gov/pubmed/10675341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.719 |
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