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On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction

In response to alkaline ambient pH, the Aspergillus nidulans PacC transcription factor mediating pH regulation of gene expression is activated by proteolytic removal of a negative-acting C–terminal domain. We demonstrate interactions involving the ∼150 C–terminal PacC residues and two regions locate...

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Detalles Bibliográficos
Main Authors: Espeso, Eduardo A., Roncal, Tomás, Díez, Eliecer, Rainbow, Lynne, Bignell, Elaine, Álvaro, Josué, Suárez, Teresa, Denison, Steven H., Tilburn, Joan, Arst, Herbert N., Peñalva, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC305610/
https://ncbi.nlm.nih.gov/pubmed/10675341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.719
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