On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction

In response to alkaline ambient pH, the Aspergillus nidulans PacC transcription factor mediating pH regulation of gene expression is activated by proteolytic removal of a negative-acting C–terminal domain. We demonstrate interactions involving the ∼150 C–terminal PacC residues and two regions locate...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Espeso, Eduardo A., Roncal, Tomás, Díez, Eliecer, Rainbow, Lynne, Bignell, Elaine, Álvaro, Josué, Suárez, Teresa, Denison, Steven H., Tilburn, Joan, Arst, Herbert N., Peñalva, Miguel A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2000
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.4.719
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