On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction

In response to alkaline ambient pH, the Aspergillus nidulans PacC transcription factor mediating pH regulation of gene expression is activated by proteolytic removal of a negative-acting C–terminal domain. We demonstrate interactions involving the ∼150 C–terminal PacC residues and two regions locate...

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Pubblicato in:	EMBO J
Autori principali:	Espeso, Eduardo A., Roncal, Tomás, Díez, Eliecer, Rainbow, Lynne, Bignell, Elaine, Álvaro, Josué, Suárez, Teresa, Denison, Steven H., Tilburn, Joan, Arst, Herbert N., Peñalva, Miguel A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2000
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.4.719
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