Virulence Comparisons of Aspergillus nidulans Mutants Are Confounded by the Inflammatory Response of p47(phox)(−/−) Mice

While investigating the requirement for phagosomal alkalinization in the host defense against pulmonary aspergillosis, we observed high morbidity of p47(phox)(−/−) mice infected with pH-insensitive Aspergillus nidulans mutants despite a paucity of fungal growth. Fatal infection also resulted from a...

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Bibliografiska uppgifter
Huvudupphovsmän: Bignell, Elaine, Negrete-Urtasun, Susana, Calcagno, Ana Maria, Arst, Herbert N., Rogers, Tom, Haynes, Ken
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2005
Ämnen:
Fungal and Parasitic Infections
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201179/
https://ncbi.nlm.nih.gov/pubmed/16041040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.5204-5207.2005
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