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Peroral Amphotericin B Polymer Nanoparticles Lead to Comparable or Superior In Vivo Antifungal Activity to That of Intravenous Ambisome(®) or Fungizone™

BACKGROUND: Despite advances in the treatment, the morbidity and mortality rate associated with invasive aspergillosis remains unacceptably high (70–90%) in immunocompromised patients. Amphotericin B (AMB), a polyene antibiotic with broad spectrum antifungal activity appears to be a choice of treatm...

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書誌詳細
主要な著者: Italia, Jagdishbhai L., Sharp, Andrew, Carter, Katharine C., Warn, Peter, Kumar, M. N. V. Ravi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188565/
https://ncbi.nlm.nih.gov/pubmed/21998690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025744
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