Epstein-Barr Virus Recombinants from BC-1 and BC-2 Can Immortalize Human Primary B Lymphocytes with Different Levels of Efficiency and in the Absence of Coinfection by Kaposi's Sar...

Por Aguirre, Andrew J., Robertson, Erle S.
Publicado em 2000

Synthetic Lethal Vulnerabilities in KRAS-Mutant Cancers

Por Aguirre, Andrew J., Hahn, William C.
Publicado no Cold Spring Harb Perspect Med (2018)

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

Por Aguirre, Andrew J., Bardeesy, Nabeel, Sinha, Manisha, Lopez, Lyle, Tuveson, David A., Horner, James, Redston, Mark S., DePinho, Ronald A.
Publicado em 2003

High-resolution characterization of the pancreatic adenocarcinoma genome

Por Aguirre, Andrew J., Brennan, Cameron, Bailey, Gerald, Sinha, Raktim, Feng, Bin, Leo, Christopher, Zhang, Yunyu, Zhang, Jean, Gans, Joseph D., Bardeesy, Nabeel, Cauwels, Craig, Cordon-Cardo, Carlos, Redston, Mark S., DePinho, Ronald A., Chin, Lynda
Publicado em 2004

Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse

Por Bardeesy, Nabeel, Aguirre, Andrew J., Chu, Gerald C., Cheng, Kuang-hung, Lopez, Lyle V., Hezel, Aram F., Feng, Bin, Brennan, Cameron, Weissleder, Ralph, Mahmood, Umar, Hanahan, Douglas, Redston, Mark S., Chin, Lynda, DePinho, Ronald A.
Publicado em 2006

High-resolution genomic profiles of human lung cancer

Por Tonon, Giovanni, Wong, Kwok-Kin, Maulik, Gautam, Brennan, Cameron, Feng, Bin, Zhang, Yunyu, Khatry, Deepak B., Protopopov, Alexei, You, Mingjian James, Aguirre, Andrew J., Martin, Eric S., Yang, Zhaohui, Ji, Hongbin, Chin, Lynda, DePinho, Ronald A.
Publicado em 2005

ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition

Por Wang, Belinda, Krall, Elsa Beyer, Aguirre, Andrew James, Kim, Miju, Widlund, Hans Ragnar, Doshi, Mihir Bhavik, Sicinska, Ewa, Sulahian, Rita, Goodale, Amy, Cowley, Glenn Spencer, Piccioni, Federica, Doench, John Gerard, Root, David Edward, Hahn, William Chun
Publicado no Cell Rep (2017)

ARID1B is a specific vulnerability in ARID1A-mutant cancers

Por Helming, Katherine C., Wang, Xiaofeng, Wilson, Boris G., Vazquez, Francisca, Haswell, Jeffrey R., Manchester, Haley E., Kim, Youngha, Kryukov, Gregory V., Ghandi, Mahmoud, Aguirre, Andrew J., Jagani, Zainab, Wang, Zhong, Garraway, Levi A., Hahn, William C., Roberts, Charles W. M.
Publicado em 2014

PIK3CA mutant tumors depend on oxoglutarate dehydrogenase

Por Ilic, Nina, Birsoy, Kıvanç, Aguirre, Andrew J., Kory, Nora, Pacold, Michael E., Singh, Shambhavi, Moody, Susan E., DeAngelo, Joseph D., Spardy, Nicole A., Freinkman, Elizaveta, Weir, Barbara A., Tsherniak, Aviad, Cowley, Glenn S., Root, David E., Asara, John M., Vazquez, Francisca, Widlund, Hans R., Sabatini, David M., Hahn, William C.
Publicado no Proc Natl Acad Sci U S A (2017)

Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells

Por Gu, Mancang, Nishihara, Reiko, Chen, Yang, Li, Wanwan, Shi, Yan, Masugi, Yohei, Hamada, Tsuyoshi, Kosumi, Keisuke, Liu, Li, da Silva, Annacarolina, Nowak, Jonathan A., Twombly, Tyler, Du, Chunxia, Koh, Hideo, Li, Wenbin, Meyerhardt, Jeffrey A., Wolpin, Brian M., Giannakis, Marios, Aguirre, Andrew J., Bass, Adam J., Drew, David A., Chan, Andrew T., Fuchs, Charles S., Qian, Zhi Rong, Ogino, Shuji
Publicado no Oncotarget (2017)

KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer

Por Krall, Elsa B, Wang, Belinda, Munoz, Diana M, Ilic, Nina, Raghavan, Srivatsan, Niederst, Matthew J, Yu, Kristine, Ruddy, David A, Aguirre, Andrew J, Kim, Jong Wook, Redig, Amanda J, Gainor, Justin F, Williams, Juliet A, Asara, John M, Doench, John G, Janne, Pasi A, Shaw, Alice T, McDonald III, Robert E, Engelman, Jeffrey A, Stegmeier, Frank, Schlabach, Michael R, Hahn, William C
Publicado no eLife (2017)

Correction: KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer

Por Krall, Elsa Beyer, Wang, Belinda, Munoz, Diana M, Ilic, Nina, Raghavan, Srivatsan, Niederst, Matthew J, Yu, Kristine, Ruddy, David A, Aguirre, Andrew J, Kim, Jong Wook, Redig, Amanda J, Gainor, Justin F, Williams, Juliet A, Asara, John M, Doench, John G, Janne, Pasi A, Shaw, Alice T, McDonald III, Robert E, Engelman, Jeffrey A, Stegmeier, Frank, Schlabach, Michael R, Hahn, William C
Publicado no eLife (2017)

Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer

Por Bullman, Susan, Pedamallu, Chandra S., Sicinska, Ewa, Clancy, Thomas E., Zhang, Xiaoyang, Cai, Diana, Neuberg, Donna, Huang, Katherine, Guevara, Fatima, Nelson, Timothy, Chipashvili, Otari, Hagan, Timothy, Walker, Mark, Ramachandran, Aruna, Diosdado, Begoña, Serna, Garazi, Mulet, Nuria, Landolfi, Stefania, Cajal, Santiago Ramon y, Fasani, Roberta, Aguirre, Andrew J., Ng, Kimmie, Élez, Elena, Ogino, Shuji, Tabernero, Josep, Fuchs, Charles S., Hahn, William C., Nuciforo, Paolo, Meyerson, Matthew
Publicado no Science (2017)

Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer

Por Kimmelman, Alec C., Hezel, Aram F., Aguirre, Andrew J., Zheng, Hongwu, Paik, Ji-hye, Ying, Haoqiang, Chu, Gerald C., Zhang, Jean X., Sahin, Ergun, Yeo, Giminna, Ponugoti, Aditya, Nabioullin, Roustem, Deroo, Scott, Yang, Shenghong, Wang, Xiaoxu, McGrath, John P., Protopopova, Marina, Ivanova, Elena, Zhang, Jianhua, Feng, Bin, Tsao, Ming S., Redston, Mark, Protopopov, Alexei, Xiao, Yonghong, Futreal, P. Andrew, Hahn, William C., Klimstra, David S., Chin, Lynda, DePinho, Ronald A.
Publicado em 2008

Genomic copy number dictates a gene-independent cell response to CRISPR-Cas9 targeting

Por Aguirre, Andrew J., Meyers, Robin M., Weir, Barbara A., Vazquez, Francisca, Zhang, Cheng-Zhong, Ben-David, Uri, Cook, April, Ha, Gavin, Harrington, William F., Doshi, Mihir B., Kost-Alimova, Maria, Gill, Stanley, Xu, Han, Ali, Levi D., Jiang, Guozhi, Pantel, Sasha, Lee, Yenarae, Goodale, Amy, Cherniack, Andrew D., Oh, Coyin, Kryukov, Gregory, Cowley, Glenn S., Garraway, Levi A., Stegmaier, Kimberly, Roberts, Charles W., Golub, Todd R., Meyerson, Matthew, Root, David E., Tsherniak, Aviad, Hahn, William C.
Publicado no Cancer Discov (2016)

Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States

Por Kim, Jong Wook, Abudayyeh, Omar O., Yeerna, Huwate, Yeang, Chen-Hsiang, Stewart, Michelle, Jenkins, Russell W., Kitajima, Shunsuke, Konieczkowski, David J., Medetgul-Ernar, Kate, Cavazos, Taylor, Mah, Clarence, Ting, Stephanie, Van Allen, Eliezer M., Cohen, Ofir, Mcdermott, John, Damato, Emily, Aguirre, Andrew J., Liang, Jonathan, Liberzon, Arthur, Alexe, Gabriella, Doench, John, Ghandi, Mahmoud, Vazquez, Francisca, Weir, Barbara A., Tsherniak, Aviad, Subramanian, Aravind, Meneses-Cime, Karina, Park, Jason, Clemons, Paul, Garraway, Levi A., Thomas, David, Boehm, Jesse S., Barbie, David A., Hahn, William C., Mesirov, Jill P., Tamayo, Pablo
Publicado no Cell Syst (2017)

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Por Viswanathan, Vasanthi S., Ryan, Matthew J., Dhrav, Harshil D., Gill, Shubhroz, Eichhoff, Ossia M., Seashore-Ludlow, Brinton, Kaffenberger, Samuel D., Eaton, John K., Shimada, Kenichi, Aguirre, Andrew J., Viswanathan, Srinivas R., Chattopadhyay, Shrikanta, Tamayo, Pablo, Yang, Wan Seok, Rees, Matthew G., Chen, Sixun, Boskovic, Zarko V, Javaid, Sarah, Huang, Cherrie, Wu, Xiaoyun, Tseng, Yuen-Yi, Roider, Elisabeth M., Gao, Dong, Cleary, James M., Wolpin, Brian M., Mesirov, Jill P., Haber, Daniel A., Engelman, Jeffrey A., Boehm, Jesse S., Kotz, Joanne D., Hon, Cindy S., Chen, YU, Hahn, William C., Levesque, Mitchell P., Doench, John G., Berens, Michael E., Shamji, Alykhan F., Clemons, Paul A., Stockwell, Brent R., Schreiber, Stuart L.
Publicado no Nature (2017)

Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma

Por Qian, Zhi Rong, Rubinson, Douglas A., Nowak, Jonathan A., Morales-Oyarvide, Vicente, Dunne, Richard F., Kozak, Margaret M., Welch, Marisa W., Brais, Lauren K., Da Silva, Annacarolina, Li, Tingting, Li, Wanwan, Masuda, Atsuhiro, Yang, Juhong, Shi, Yan, Gu, Mancang, Masugi, Yohei, Bui, Justin, Zellers, Caitlin L., Yuan, Chen, Babic, Ana, Khalaf, Natalia, Aguirre, Andrew, Ng, Kimmie, Miksad, Rebecca A., Bullock, Andrea J., Chang, Daniel T., Tseng, Jennifer F., Clancy, Thomas E., Linehan, David C., Findeis-Hosey, Jennifer J., Doyle, Leona A., Thorner, Aaron R., Ducar, Matthew, Wollison, Bruce, Laing, Angelica, Hahn, William C., Meyerson, Matthew, Fuchs, Charles S., Ogino, Shuji, Hornick, Jason L., Hezel, Aram F., Koong, Albert C., Wolpin, Brian M.
Publicado no JAMA Oncol (2017)