Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells

Evidence suggests that nonsteroidal anti-inflammatory drug aspirin (acetylsalicylic acid) may improve patient survival in PIK3CA-mutant colorectal carcinoma, but not in PIK3CA-wild-type carcinoma. However, whether aspirin directly influences the viability of PIK3CA-mutant colon cancer cells is poorl...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gu, Mancang, Nishihara, Reiko, Chen, Yang, Li, Wanwan, Shi, Yan, Masugi, Yohei, Hamada, Tsuyoshi, Kosumi, Keisuke, Liu, Li, da Silva, Annacarolina, Nowak, Jonathan A., Twombly, Tyler, Du, Chunxia, Koh, Hideo, Li, Wenbin, Meyerhardt, Jeffrey A., Wolpin, Brian M., Giannakis, Marios, Aguirre, Andrew J., Bass, Adam J., Drew, David A., Chan, Andrew T., Fuchs, Charles S., Qian, Zhi Rong, Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675640/
https://ncbi.nlm.nih.gov/pubmed/29152088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20972
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