Smoking and Risk of Colorectal Cancer Sub-Classified by Tumor-Infiltrating T Cells

BACKGROUND: Evidence indicates not only carcinogenic effect of cigarette smoking but also its immunosuppressive effect. We hypothesized that the association of smoking with colorectal cancer risk might be stronger for tumors with lower anti-tumor adaptive immune response. METHODS: During follow-up o...

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Publicado en:J Natl Cancer Inst
Autores principales: Hamada, Tsuyoshi, Nowak, Jonathan A, Masugi, Yohei, Drew, David A, Song, Mingyang, Cao, Yin, Kosumi, Keisuke, Mima, Kosuke, Twombly, Tyler S, Liu, Li, Shi, Yan, da Silva, Annacarolina, Gu, Mancang, Li, Wanwan, Nosho, Katsuhiko, Keum, NaNa, Giannakis, Marios, Meyerhardt, Jeffrey A, Wu, Kana, Wang, Molin, Chan, Andrew T, Giovannucci, Edward L, Fuchs, Charles S, Nishihara, Reiko, Zhang, Xuehong, Ogino, Shuji
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335108/
https://ncbi.nlm.nih.gov/pubmed/30312431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djy137
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