Smoking and Risk of Colorectal Cancer Sub-Classified by Tumor-Infiltrating T Cells

BACKGROUND: Evidence indicates not only carcinogenic effect of cigarette smoking but also its immunosuppressive effect. We hypothesized that the association of smoking with colorectal cancer risk might be stronger for tumors with lower anti-tumor adaptive immune response. METHODS: During follow-up o...

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Publicado no:J Natl Cancer Inst
Main Authors: Hamada, Tsuyoshi, Nowak, Jonathan A, Masugi, Yohei, Drew, David A, Song, Mingyang, Cao, Yin, Kosumi, Keisuke, Mima, Kosuke, Twombly, Tyler S, Liu, Li, Shi, Yan, da Silva, Annacarolina, Gu, Mancang, Li, Wanwan, Nosho, Katsuhiko, Keum, NaNa, Giannakis, Marios, Meyerhardt, Jeffrey A, Wu, Kana, Wang, Molin, Chan, Andrew T, Giovannucci, Edward L, Fuchs, Charles S, Nishihara, Reiko, Zhang, Xuehong, Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335108/
https://ncbi.nlm.nih.gov/pubmed/30312431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djy137
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