Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status

PURPOSE: Blockade of the programmed cell death 1 (PDCD1, PD-1) immune checkpoint pathway can improve clinical outcomes in various malignancies. Evidence suggests that aspirin (a widely used nonsteroidal anti-inflammatory drug) not only prolongs colorectal cancer survival, but can also activate T cel...

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Publicat a:J Clin Oncol
Autors principals: Hamada, Tsuyoshi, Cao, Yin, Qian, Zhi Rong, Masugi, Yohei, Nowak, Jonathan A., Yang, Juhong, Song, Mingyang, Mima, Kosuke, Kosumi, Keisuke, Liu, Li, Shi, Yan, da Silva, Annacarolina, Gu, Mancang, Li, Wanwan, Keum, NaNa, Zhang, Xuehong, Wu, Kana, Meyerhardt, Jeffrey A., Giovannucci, Edward L., Giannakis, Marios, Rodig, Scott J., Freeman, Gordon J., Nevo, Daniel, Wang, Molin, Chan, Andrew T., Fuchs, Charles S., Nishihara, Reiko, Ogino, Shuji
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2017
Matèries:
ORIGINAL REPORTS
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455595/
https://ncbi.nlm.nih.gov/pubmed/28406723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.70.7547
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