Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status

PURPOSE: Blockade of the programmed cell death 1 (PDCD1, PD-1) immune checkpoint pathway can improve clinical outcomes in various malignancies. Evidence suggests that aspirin (a widely used nonsteroidal anti-inflammatory drug) not only prolongs colorectal cancer survival, but can also activate T cel...

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Bibliografiske detaljer
Udgivet i:J Clin Oncol
Main Authors: Hamada, Tsuyoshi, Cao, Yin, Qian, Zhi Rong, Masugi, Yohei, Nowak, Jonathan A., Yang, Juhong, Song, Mingyang, Mima, Kosuke, Kosumi, Keisuke, Liu, Li, Shi, Yan, da Silva, Annacarolina, Gu, Mancang, Li, Wanwan, Keum, NaNa, Zhang, Xuehong, Wu, Kana, Meyerhardt, Jeffrey A., Giovannucci, Edward L., Giannakis, Marios, Rodig, Scott J., Freeman, Gordon J., Nevo, Daniel, Wang, Molin, Chan, Andrew T., Fuchs, Charles S., Nishihara, Reiko, Ogino, Shuji
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2017
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ORIGINAL REPORTS
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455595/
https://ncbi.nlm.nih.gov/pubmed/28406723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.70.7547
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